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Nickel‐Catalyzed Direct Coupling of Allylic Alcohols with Organoboron Reagents
Author(s) -
Wang Gaonan,
Gan Yi,
Liu Yuanhong
Publication year - 2018
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201800237
Subject(s) - chemistry , allylic rearrangement , catalysis , reagent , nickel , organic chemistry , organoboron compounds , coupling (piping) , combinatorial chemistry , base (topology) , metallurgy , materials science , mathematical analysis , mathematics
The direct coupling of allylic alcohols with arylboronic acids or their derivatives catalyzed by Ni(cod) 2 in the presence of a catalytic amount of base has been developed. A wide variety of allylic substrates or arylboronic acids turned out to be applicable to this catalytic system. The present method does not require the use of ligands for stabilizing the nickel catalyst in most cases or additional activators for activation of allylic alcohols.