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Electrochemical Intramolecular C—H/O—H Cross‐Coupling of 2‐Arylbenzoic Acids
Author(s) -
Shao Ailong,
Li Na,
Gao Yong,
Zhan Jirui,
Chiang ChienWei,
Lei Aiwen
Publication year - 2018
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201800031
Subject(s) - chemistry , intramolecular force , electrochemistry , aqueous solution , natural product , electrolyte , combinatorial chemistry , oxidative coupling of methane , stereochemistry , medicinal chemistry , organic chemistry , electrode , catalysis
A synthetic protocol to lactones by electro‐oxidative induced C—H activation of 2‐arylbenzoic acids has been developed. By using Na 2 SO 4 aqueous solution as a cheap and green supporting electrolyte, different 2‐arylbenzoic acids could provide the corresponding lactones in 30%—90% yields. This reaction could be conducted on a gram scale with a good efficiency as well as a high utility for natural product synthesis.
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