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Decarboxylative Fluorination of Arylcarboxylic Acids Promoted by ortho ‐Hydroxy and Amino Groups
Author(s) -
Wang Dinghai,
Yuan Zheliang,
Liu Qilun,
Chen Pinhong,
Liu Guosheng
Publication year - 2018
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201800016
Subject(s) - chemistry , amino acid , salicylic acid , group (periodic table) , decarboxylation , transformation (genetics) , organic chemistry , stereochemistry , medicinal chemistry , catalysis , biochemistry , gene
A novel decarboxylative fluorination process has been developed for the synthesis of ortho ‐hydroxy/amino arylfluorides from salicylic acid analogs, in which the ortho ‐hydroxy/amino group plays an important role in the transformation. In addition, various arylfluorides are obtained in good to excellent yields under mild conditions.