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Back Cover: Asymmetric Synthesis of Chiral α ‐Substituted Mercaptoglycine Derivatives via α ‐Sulfenylation of Ni( II ) Complex of Glycine and S ‐Substituted 4‐Methylbenzenesulfonothioate (Chin. J. Chem. 9/2017)
Author(s) -
Li Jia,
Song Xiaohan,
Zhou Shengbin,
Wang Jiang,
Liu Hong
Publication year - 2017
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201770095
Subject(s) - chemistry , enantiomer , scope (computer science) , nickel , glycine , chin , cover (algebra) , stereoselectivity , combinatorial chemistry , stereochemistry , yield (engineering) , amino acid , chirality (physics) , organic chemistry , catalysis , biochemistry , materials science , chiral symmetry breaking , computer science , engineering , quark , quantum mechanics , nambu–jona lasinio model , metallurgy , programming language , medicine , mechanical engineering , physics , anatomy
The back cover picture shows the asymmetric synthesis of α ‐substituted mercaptoglycine via nickel(II) complex. The α ‐substituted mercaptoglycine is an important framework of various peptide drugs and nickel(II) complex can be utilized to generate single enantiomer of α ‐substituted amino acid efficiently. This work establishes an efficient method to access α ‐substituted mercaptoglycine with good yield and high stereoselectivity, which can promote the design of new peptide drugs in a broad scope. More details are discussed in the article by Wang et al. on page 1383‐1390.