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Construction of Multi‐Substituted Benzenes via NHC‐Catalyzed Reactions of Carboxylic Esters
Author(s) -
Wu Jichang,
Mou Chengli,
Chi Yonggui Robin
Publication year - 2018
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201700773
Subject(s) - chemistry , carbene , catalysis , aldehyde , benzene , combinatorial chemistry , organic chemistry , reaction conditions
A carbene‐catalyzed ester activation reaction for the synthesis of multi‐substituted benzenes is disclosed. Tetra‐substituted benzene compounds are efficiently synthesized through this methodology.