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One‐Pot Synthesis of 4‐Aryl‐ NH ‐1,2,3‐Triazoles through Three‐Component Reaction of Aldehydes, Nitroalkanes and NaN 3
Author(s) -
Hui Rongrong,
Zhao Mina,
Chen Ming,
Ren Zhihui,
Guan Zhenghui
Publication year - 2017
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201700367
Subject(s) - chemistry , component (thermodynamics) , aryl , reaction conditions , combinatorial chemistry , medicinal chemistry , organic chemistry , catalysis , alkyl , physics , thermodynamics
A one‐pot three‐component reaction of aldehydes, nitroalkanes and NaN 3 for the synthesis of NH ‐1,2,3‐triazoles has been developed. The reaction provides a safe, efficient and step‐economic approach for the synthesis of various NH ‐1,2,3‐triazoles in good to excellent yields.