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Construction of Redox Responsive Vesicles Based on a Supra‐Amphiphile for Enzyme Confinement
Author(s) -
Pan Tiezheng,
Zou Huixin,
Sun Hongcheng,
Liu Yao,
Liu Shengda,
Luo Quan,
Dong Zeyuan,
Xu Jiayun,
Liu Junqiu
Publication year - 2017
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201600772
Subject(s) - chemistry , vesicle , amphiphile , ferrocene , redox , dynamic light scattering , biocompatibility , nanotechnology , biophysics , copolymer , biochemistry , organic chemistry , nanoparticle , membrane , materials science , electrode , electrochemistry , biology , polymer
Redox responsive vesicles were constructed based on self‐assembly of a supra‐amphiphile built by the host‐ guest interaction between β ‐cyclodextrin and a ferrocene derivative. The structure and destruction‐reconstruction reversibility of the “smart” vesicles were clearly characterized by electron microscopy and dynamic light scattering. Notably, these vesicles were proved to be capable of controlled release function and bringing protease resistance to the enzyme, showing great biocompatibility and promising applications.