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Metal‐Free Oxidative Decarboxylative Acylation/Ring Expansion of Vinylcyclobutanols with α ‐Keto Acids by Visible Light Photoredox Catalysis
Author(s) -
Zhang JinJiang,
Cheng YuanBo,
Duan XinHua
Publication year - 2017
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201600729
Subject(s) - chemistry , decarboxylation , hypervalent molecule , acylation , reagent , catalysis , ring (chemistry) , photoredox catalysis , oxidative decarboxylation , visible spectrum , functional group , tandem , oxidative phosphorylation , iodine , combinatorial chemistry , organic chemistry , photochemistry , photocatalysis , biochemistry , physics , polymer , materials science , optoelectronics , composite material
A metal‐free visible‐light‐mediated decarboxylative acylation/ring expansion of vinylcyclobutanols with α ‐keto acids has been developed. Hypervalent iodine reagent was found to be important for promoting decarboxylation of α ‐keto acids in this tandem radical process. This protocol has been successfully applied to synthesis of a variety of substituted 1,4‐dicarbonyl compounds and tolerated some functional groups well.