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Synthesis of 1,3,4,6‐Tetra‐ O ‐acetyl‐ l ‐gulose
Author(s) -
Che Rui,
Liu Xingui,
Lu Wei
Publication year - 2017
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201600658
Subject(s) - chemistry , tetra , disaccharide , yield (engineering) , stereochemistry , combinatorial chemistry , medicinal chemistry , thermodynamics , physics
Abstract A novel, practical and concise synthesis of 1,3,4,6‐tetra‐ O ‐acetyl‐ l‐ gulose is described, using d ‐glucuronolactone as the starting material and other inexpensive and readily available agents (22% overall yield in 9 steps). With this method, the synthesis of l‐ gulose and the tumor‐targeting disaccharide of BLMs can be more efficient and convenient.