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Nanogels as Contrast Agents for Molecular Imaging
Author(s) -
Zhu Jianzhi,
Sun Wenjie,
Shi Xiangyang
Publication year - 2016
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201500743
Subject(s) - biocompatibility , chemistry , molecular imaging , nanotechnology , magnetic resonance imaging , surface modification , modality (human–computer interaction) , optical imaging , biomedical engineering , materials science , radiology , computer science , optics , artificial intelligence , organic chemistry , medicine , physics , microbiology and biotechnology , in vivo , biology
Nanogels (NGs) as soft nanosized materials have gained a variety of interests in biomedical fields. The versatile NG scaffolds with 3‐dimensional spherical shape, high loading efficiency, tunable surface functionalization, and excellent biocompatibility afford their uses as carrier to load mono‐ or multi‐mode molecular imaging contrast agents (CAs). This review summarizes the synthesis routes and applications of NGs as CAs for molecular imaging applications including magnetic resonance (MR), computed tomography (CT), radionuclide, optical, and dual/multi‐modality imaging.