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BF 3 ·Et 2 O Promoted Sulfuration of Steroidal Sapogenins
Author(s) -
Wang Jun,
Wu Jingjing,
Tian Weisheng
Publication year - 2015
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201500300
Subject(s) - chemistry , sapogenin , ring (chemistry) , sulfur , hydrogen sulfide , medicinal chemistry , sulfide , stereochemistry , organic chemistry , medicine , alternative medicine , pathology
A reaction between steroidal sapogenins and hydrogen sulfide promoted by BF 3 ·Et 2 O is described. The thiodiosgenin and thiotigogenin comprising a sulfur atom on the F ring can be easily afforded in one step under this mild reaction condition. Furthermore, a hypothetical mechanism is also shown.