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An Environmentally Benign Catalytic Method for Versatile Synthesis of 1,4‐Dihydropyridines via Multicomponent Reactions
Author(s) -
Cao Shuo,
Zhong Shanshan,
Hu Changfeng,
Wan JiePing,
Wen Chengping
Publication year - 2015
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201500195
Subject(s) - chemistry , catalysis , combinatorial chemistry , organic chemistry , environmentally friendly , reaction conditions , lactic acid , bacteria , ecology , genetics , biology
The synthesis of diverse 1,4‐dihydropyridines have been achieved via the multicomponent reactions of aldehydes, enaminones and amines. The reactions have been smoothly performed in water to provide all products with moderate to excellent yields by using lactic acid as a green catalyst.