N ‐Heterocyclic Carbene‐Catalyzed All Carbon‐[4+2] Cyclocondensation of  α , β ‐Unsaturated Acyl Chlorides with 3‐Alkylenyloxindoles | Zendy

Shen Litao | Zendy; Jia Wenqiang | Zendy; Ye Song | Zendy

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N ‐Heterocyclic Carbene‐Catalyzed All Carbon‐[4+2] Cyclocondensation of α , β ‐Unsaturated Acyl Chlorides with 3‐Alkylenyloxindoles

Author(s) -

Shen Litao,

Jia Wenqiang,

Ye Song

Publication year - 2014

Publication title -

chinese journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 1001-604X

DOI - 10.1002/cjoc.201400411

Subject(s) - chemistry , carbene , catalysis , yield (engineering) , carbon fibers , organic chemistry , medicinal chemistry , materials science , composite number , metallurgy , composite material

Although the NHC‐catalyzed cyclization reactions have been well established for the synthesis of various heterocycles, the corresponding all carbon cyclization reaction for the synthesis of carbocycles is far less established. In this note, the NHC‐catalyzed all carbon [4+2] cyclocondensation of α , β ‐unsaturated acyl chlorides and 3‐alkenyloxindoles was developed to give the corresponding spirocarbocyclic oxindoles in good yield with good to high diastereoselectivities.

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