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N ‐Heterocyclic Carbene‐Catalyzed All Carbon‐[4+2] Cyclocondensation of α , β ‐Unsaturated Acyl Chlorides with 3‐Alkylenyloxindoles
Author(s) -
Shen Litao,
Jia Wenqiang,
Ye Song
Publication year - 2014
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201400411
Subject(s) - chemistry , carbene , catalysis , yield (engineering) , carbon fibers , organic chemistry , medicinal chemistry , materials science , composite number , metallurgy , composite material
Abstract Although the NHC‐catalyzed cyclization reactions have been well established for the synthesis of various heterocycles, the corresponding all carbon cyclization reaction for the synthesis of carbocycles is far less established. In this note, the NHC‐catalyzed all carbon [4+2] cyclocondensation of α , β ‐unsaturated acyl chlorides and 3‐alkenyloxindoles was developed to give the corresponding spirocarbocyclic oxindoles in good yield with good to high diastereoselectivities.