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Palladium‐Catalyzed Cross‐Coupling of Fluorinated Vinyl Chlorides with Terminal Alkynes: A General Protocol to Fluorinated Enynes
Author(s) -
Chen Sheng,
Xu Chunfa,
Lu Long,
Shen Qilong
Publication year - 2013
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201300352
Subject(s) - chemistry , conjugated system , amine gas treating , catalysis , palladium , functional group , coupling (piping) , vinyl chloride , terminal (telecommunication) , chloride , coupling reaction , combinatorial chemistry , organic chemistry , polymer chemistry , copolymer , mechanical engineering , telecommunications , polymer , computer science , engineering
Abstract An efficient and cost‐effective method for the preparation of fluorinated conjugated enynes was described. The method was compatible with a variety of functional groups such as chloride, amine, cyano and ester group. The method could also be extended to the coupling of ( R , Z )‐3‐(2‐chloro‐1,2‐difluorovinyl)‐4‐alkyloxazolidin‐2‐one ( 3 ) with moderate yields.