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Iron(III) Chloride Catalyzed Oxidative Coupling Reaction of 1,2‐Diarylethylene Derivatives
Author(s) -
Ji Derong,
Su Lidan,
Zhao Keqing,
Wang Biqin,
Hu Ping,
Feng Chun,
Xiang Shikai,
Yang Hua,
Zhang Chenggang
Publication year - 2013
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201300308
Subject(s) - phenanthrenes , chemistry , oxidative coupling of methane , yield (engineering) , intramolecular force , catalysis , oxidative phosphorylation , chloride , coupling reaction , medicinal chemistry , coupling (piping) , reaction conditions , organic chemistry , phenanthrene , mechanical engineering , materials science , biochemistry , engineering , metallurgy
A nontoxic FeCl 3 catalyzed intramolecular oxidative coupling reaction was developed for mild synthesis of a series of phenanthrenes with different substituents. The method involves cross dehydrogenative coupling of a variety of 1,2‐diarylethylene derivatives with di‐ tert ‐butylperoxide (DTBP) as a sole oxidant at room temperature in CH 2 Cl 2 /TFA (9:1 V / V ) to yield phenanthrenes in good to excellent yields.