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Synthesis and Antioxidant Activities of Novel 4,4′‐Arylmethylene‐bis(1 H ‐pyrazole‐5‐ol)s from Lignin
Author(s) -
Yang Xiaohui,
Zhang Pinghu,
Zhou Yonghong,
Wang Junsong,
Liu Hongjun
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201280009
Subject(s) - chemistry , trolox , dpph , abts , antioxidant , organic chemistry , lignin , nuclear chemistry
A series of novel bispyrazoles joined by arylmethylene at C‐4 position were synthesized with aromatic aldehydes obtained from lignin and screened for their in vitro antioxidant activities by N , N ‐diphenyl‐ N′ ‐picrylhydrazyl (DPPH) and 2,2′‐azino‐bis(3‐ethylenzothiazoline‐sulphonic acid) diammonium salt (ABTS + ) radical scavenging assays. All of these compounds exhibited good DPPH and ABST + radical scavenging activities as compared to the standard, Trolox, which suggested their potential as promising agents for curing tumors or other free radical‐related diseases.