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Syntheses, Supramolecular Structures and Antibacterial Activities of Five Helical Transition Complexes with 5‐Chloro‐1‐phenyl‐1 H ‐pyrazole‐3,4‐dicarboxylic Acid
Author(s) -
Liu Hong,
Liu Chongbo,
Gong Yunnan,
Wang Yuhua,
Wen Huiliang
Publication year - 2013
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201201009
Subject(s) - chemistry , supramolecular chemistry , pyrazole , stereochemistry , hydrogen bond , transition metal , bacillus subtilis , monomer , crystallography , escherichia coli , bacteria , molecule , polymer , organic chemistry , crystal structure , biochemistry , catalysis , biology , genetics , gene
Five new transition metal complexes [Cu(HL) 2 (H 2 O) 2 ] ( 1 ), [Cu(HL) 2 (phen)] ( 2 ), [Cu(HL) 2 (H 2 O)] 2 (4,4′‐bipy) ( 3 ), [Zn(HL) 2 (H 2 O) 2 ]·(4,4′‐bipy) ( 4 ), [Ag(HL)(4,4′‐bipy)] n ( 5 ), (H 2 L=5‐chloro‐1‐phenyl‐1 H ‐pyrazole‐3,4‐dicarboxylic acid, phen=1,10‐phenanthroline; 4,4′‐bipy=4,4′‐bipyridine) have been synthesized and characterized. Complexes 1 , 2 and 4 exhibit monomeric structures, 3 shows a dinuclear structure, 5 displays 1D chain structure, and all extend to 3D supramolecular network via rich hydrogen bonds. Complexes 1 , 2 , 3 , 5 comprise single helical chains, while complex 4 generates quadruple‐stranded helical chains. Furthermore, the antibacterial activities of the titled complexes against bacterial species, three Gram positive bacteria ( Staphylococcus aureus , Bacillus subtilis and Candida albicans ) and two Gram negative bacteria ( Escherichia coli and Pseudomonas aeruginosa ) were studied and compared to the activities of free ligands by using the microdilution method.