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Fe 3 O 4 Modified Up‐Conversion Luminescent Nanocrystals for Biological Applications
Author(s) -
Hou Yu,
Yin Zifei,
Xin Hailiang,
Su Yonghua,
Yang Huagui
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200854
Subject(s) - nanocrystal , luminescence , superparamagnetism , x ray photoelectron spectroscopy , nucleation , chemistry , transmission electron microscopy , nanotechnology , nanoparticle , nanocomposite , chemical engineering , materials science , magnetization , optoelectronics , organic chemistry , magnetic field , physics , quantum mechanics , engineering
Magnetic‐luminescent nanocomposites have obtained a great deal of attention due to their potential applications in magnetic separation of cells, magnetic resonance imaging and luminescence imaging, and so on. Herein, a new and facile two‐step synthetic strategy was developed to prepare magnetic Fe 3 O 4 modified single crystalline up‐conversion luminescent NaYF 4 : Yb 3+ , Er 3+ nanocrystals using Fe 3 O 4 nanoparticles as the seeds. Acting as the "nuclei" in the reaction, the presence of Fe 3 O 4 nanoparticles facilitates the formation of up‐conversion NaYF 4 : Yb 3+ , Er 3+ nanocrystals on their surfaces through heterogeneous nucleation process. The structure and properties of these multifunctional nanocrystals were characterized by transmission electron microscope (TEM), X‐ray photoelectron spectroscopy (XPS), photo luminescence (PL) and X‐ray diffraction (XRD). The results revealed that the as‐prepared multifunctional nanocrystals show dual distinct properties of up‐conversion fluorescent and superparamagnetism, which were cubic in shape and very uniform in size with an average size ranging 30–40 nm. These unique functionalities could be very attractive for biological systems, and some biological applications such as cell‐labelling were also demonstrated.