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Organocatalytic Asymmetric Branching Sequence of MBH Carbonates: Access to Chiral Benzofuran‐2(3 H )‐one Derivatives with Three Stereocenters
Author(s) -
Zhu Chuanle,
Yang Lijun,
Nie Jing,
Zheng Yan,
Ma Junan
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200809
Subject(s) - stereocenter , chemistry , branching (polymer chemistry) , sequence (biology) , benzofuran , organocatalysis , enantioselective synthesis , stereochemistry , quaternary carbon , organic chemistry , combinatorial chemistry , catalysis , biochemistry
An organocatalytic asymmetric branching sequence was realized in the presence of 10 mol% of (DHQD) 2 AQN, affording the sequential products with three stereocentres, including two quaternary carbon centres, in 47%–79% yields with 85%–99% ee .