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A General and Efficient CuBr 2 ‐Catalyzed N ‐Arylation of Secondary Acyclic Amides
Author(s) -
Wang Mangang,
Yu Hua,
You Xinwen,
Wu Jun,
Shang Zhicai
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200701
Subject(s) - chemistry , halide , toluene , aryl , catalysis , functional group , organic chemistry , medicinal chemistry , combinatorial chemistry , alkyl , polymer
A general and efficient Cu(II)‐catalyzed cross‐coupling method is reported for the preparation of acyclic tertiary amides. Generally moderate to excellent yields and functional group tolerance were obtained with secondary acyclic amides and aryl halides as substrates in toluene.