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Organocatalytic Asymmetric Double Michael Reaction of Benzofuranone with Dienones to Construct Spirocyclic Benzofuranones
Author(s) -
Luo Xiya,
Wang Liangliang,
Peng Lin,
Bai Jianfei,
Jia Lina,
Tian Fang,
Xu Xiaoying,
Wang Lixin
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200676
Subject(s) - chemistry , michael reaction , enantioselective synthesis , cinchona , yield (engineering) , organocatalysis , cinchona alkaloids , organic chemistry , stereochemistry , catalysis , materials science , metallurgy
The enantioselective double Michael reaction of benzofuranone with dienones catalyzed by Cinchona‐based primary amines was developed. A number of optically active spirocyclic benzofuranones were obtained in up to 89% yield and 91% ee .
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