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Synthesis and Application of a Full Water‐Soluble and Red‐Emitting Chemosensor Based on Phenoxazinium for Copper(II) Ions
Author(s) -
Yan Baolong,
Sun Ru,
Ge Jianfeng,
Xu Yujie,
Zhang Qianqian,
Yang Xuebo,
Lu Jianmei
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200452
Subject(s) - chemistry , fluorescence , amine gas treating , copper , ion , membrane permeability , membrane , ab initio , photochemistry , combinatorial chemistry , inorganic chemistry , organic chemistry , biochemistry , physics , quantum mechanics
A phenoxazinium‐based chemosensor ( 1 ) bearing di(2‐picolyl)amine unit was successfully synthesized. The result shows that it is a red‐emitting and full water‐soluble chemosensor for the selective detection of Cu 2+ in pure water. The fluorescence on‐off mechanism was studied by ab initio calculations. To confirm the suitability of 1 for biological applications, it was employed in the fluorescence detection of the intracellular Cu 2+ with cultured KB cells. The results indicated that 1 had good membrane permeability and could be useful for the fluorescence microscopic imaging.