Premium
Axially Chiral C 2 ‐Symmetric N ‐Heterocyclic Carbene (NHC) Palladium Complex‐Catalyzed Asymmetric Fluorination and Amination of Oxindoles
Author(s) -
Zhang Rui,
Wang De,
Xu Qin,
Jiang Jiajun,
Shi Min
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200289
Subject(s) - chemistry , carbene , palladium , catalysis , amination , enantioselective synthesis , axial symmetry , medicinal chemistry , organic chemistry , combinatorial chemistry , structural engineering , engineering
Abstract Chiral C 2 ‐symmetric N ‐heterocyclic carbene (NHC) palladium diaquo complex 5b prepared from ( S )‐BINAM was found to be a fairly effective catalyst for the enantioselective asymmetric fluorination of oxindoles to give the corresponding products in moderate enantioselectivities along with good to excellent yields.