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Efficient Regioselective Synthesis of 3‐Iodoindole N ‐Carboximidamides and N ‐Carboximidoates by a Sequential Aza‐Wittig/Iodine Induced Cyclization
Author(s) -
Nie Yibo,
Duan Zhuan,
Ding Mingwu
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200281
Subject(s) - chemistry , regioselectivity , wittig reaction , iodine , nucleophile , combinatorial chemistry , organic chemistry , medicinal chemistry , catalysis
3‐Iodoindole N ‐carboximidamides and N ‐carboximidoates 4 were prepared regioselectively via a sequential aza‐Wittig/iodine induced cyclization, starting from easily accessible 2‐alkynylphenyl iminophosphorane, isocyanates, various nucleophiles and iodine.

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