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Reductive Amination of Aldehydes and Ketones with Primary Amines by Using Lithium Amidoborane as Reducing Reagent
Author(s) -
Xu Weiliang,
Zheng Xueli,
Wu Guotao,
Chen Ping
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201200132
Subject(s) - chemistry , reductive amination , reagent , lithium (medication) , borane , amination , primary (astronomy) , reducing agent , organic chemistry , ammonia , combinatorial chemistry , catalysis , medicine , physics , astronomy , endocrinology
A variety of secondary amines were obtained in high isolated yields in the reductive amination of aldehydes and ketones by using lithium amidoborane as reducing agent. Compared to ammonia borane, lithium amidoborane has higher reducibility, and thus, exhibits faster reaction rate.