Synthesis of 1‐Aryl‐1 H ‐indazoles via a Ligand‐Free Copper‐ Catalyzed Intramolecular Amination Reaction | Zendy

Shen Fengjuan | Zendy; Li Xiaoliu | Zendy; Zhang Xiaojuan | Zendy; Qin Zhanbin | Zendy; Yin Qingmei | Zendy; Chen Hua | Zendy; Zhang Jinchao | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of 1‐Aryl‐1 H ‐indazoles via a Ligand‐Free Copper‐ Catalyzed Intramolecular Amination Reaction

Author(s) -

Shen Fengjuan,

Li Xiaoliu,

Zhang Xiaojuan,

Qin Zhanbin,

Yin Qingmei,

Chen Hua,

Zhang Jinchao

Publication year - 2011

Publication title -

chinese journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 1001-604X

DOI - 10.1002/cjoc.201190224

Subject(s) - chemistry , indazole , intramolecular force , aryl , amination , ligand (biochemistry) , catalysis , copper , intermolecular force , combinatorial chemistry , ullmann reaction , coupling reaction , organic chemistry , medicinal chemistry , molecule , biochemistry , alkyl , receptor

A general synthesis of 1‐aryl‐1‐ H ‐indazoles from o ‐halogenated aryl aldehydes or ketones and aryl hydrazines was described. This protocol included an intermolecular condensation and a ligand‐free copper‐catalyzed intramolecular Ullmann‐type coupling reaction. This method was applied to a wide range of substrates to produce the indazole products in good yields.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research