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Sodium Bisulfite: An Efficient Catalyst for Ether Formation via Dehydration of Aromatic/Aliphatic Alcohol
Author(s) -
Wang Hui,
Zhu Xingfei,
Lu Yangning,
Li Yue,
Gao Xiang
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201190220
Subject(s) - chemistry , sodium bisulfite , dehydration , bisulfite , catalysis , alcohol , organic chemistry , solvent , ether , sodium , intermolecular force , benzyl alcohol , molecule , biochemistry , gene expression , dna methylation , gene
Straightforward etherification of benzyl alcohols ( 1 ) via intermolecular dehydration can be efficiently catalyzed by sodium bisulfite under solvent‐free conditions. In the presence of 0.3 mol% or 0.6 mol% amount of sodium bisulfite, symmetric and unsymmetric ethers are prepared from the corresponding alcohols in high yields (up to 95%). Etherification of benzhydryl alcohols is also discussed.