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Electrocatalysis of Puerarin on a Nano‐CeO 2 /MWCNTs Composite Modified Electrode and Its Determination in Pharmaceutical Preparations
Author(s) -
Ji Yulan,
Wang Guangfeng,
Zhang Cuihong,
Fang Bin
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201190173
Subject(s) - dielectric spectroscopy , chemistry , cyclic voltammetry , carbon nanotube , scanning electron microscope , electrocatalyst , electrode , puerarin , nano , amperometry , nanoparticle , detection limit , chemical engineering , chronoamperometry , nuclear chemistry , electrochemistry , nanotechnology , analytical chemistry (journal) , materials science , chromatography , composite material , medicine , alternative medicine , pathology , engineering
A good route for the fabrication of CeO 2 nanoparticles (nano‐CeO 2 )/multi‐walled carbon nanotubes (MWCNTs) modified glassy carbon electrodes (GCE) was proposed. MWCNTs are used to immobilize nano‐CeO 2 . What′s more, with the addition of the MWCNTs, the agglomeration level of CeO 2 nanoparticles can be reduced, the extremely large surface area can be obtained and the electron transfer rate can be increased. The morphological characterization of nano‐CeO 2 /MWCNTs was examined by scanning electron microscopy (SEM). The performances of the nano‐CeO 2 /MWCNTs/GCE were characterized with cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and typical amperometric response ( i ‐ t ). The potential utility of the constructed electrodes was demonstrated by applying them to the analytical determination of puerarin concentration. The catalytic oxidation of puerarin has a better result on nano‐CeO 2 /MWCNTs/GCE because of the synergistic effect of nano‐CeO 2 and MWCNTs. An optimized limit of detection of 8.0×10 −9 mol/L was obtained at a signal‐to‐noise ratio of 3 and with a fast response time (within 3 s). Additionally, the nano‐CeO 2 /MWCNTs/GCE exhibited a wide linear range from 0.04 to 6.0 μmol/L and high sensitivity.