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Pyridine‐ N ‐oxide: An Efficient Organocatalyst for Ring‐Opening Reactions of Aziridines with Aryl Thiols
Author(s) -
Yang Qin,
Yin Zhenlan,
Yang Min,
Peng Yiyuan
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201190064
Subject(s) - chemistry , aryl , pyridine , pyridine n oxide , ring (chemistry) , catalysis , oxide , combinatorial chemistry , transformation (genetics) , organic chemistry , organocatalysis , medicinal chemistry , enantioselective synthesis , gene , biochemistry , alkyl
Pyridine‐ N ‐oxide serves as an efficient catalyst for the ring‐opening reactions of N ‐tosylaziridines with various aryl thiols under mild conditions. This transformation is highly effective, which gives rise to the corresponding β ‐amino sulfides in good to excellent yields.