Premium
[BMIM]Cl Catalyzed One‐Pot Synthesis of α ‐Aminophosphonate Derivatives Containing a 4‐Phenoxyquinazoline Moiety under Microwave Irradiation
Author(s) -
Bai Song,
Song Baoan,
Bhadury Pinaki S.,
Yang Song,
Hu Deyu,
Xue Wei
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201190035
Subject(s) - chemistry , moiety , microwave irradiation , catalysis , aldehyde , environmentally friendly , mannich reaction , organic chemistry , combinatorial chemistry , ecology , biology
[BMIM]Cl catalyzed three component Mannich‐type reaction of 4‐(quinazolin‐4‐yloxy)benzenamine and aldehyde with dialkyl phosphite under microwave irradiation has been described. The salient features of the reaction leading to new α ‐aminophosphonates include shorter reaction time and good yields. The method is environmentally friendly and does not require toxic catalysts or solvents. To the best of our knowledge, this is the first report for [BMIM]Cl induced one‐pot synthesis of α ‐aminophosphonate derivatives.