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A Green Route for the One‐Pot Synthesis of 1,2‐Disubstituted Benzimidazoles Using Iron(III) Phosphate under Solventless Conditions
Author(s) -
Behbahani F. K.,
Ziaei Parisa
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201180461
Subject(s) - chemistry , catalysis , condensation , aldehyde , phosphate , environmentally friendly , organic chemistry , green chemistry , solvent , condensation reaction , combinatorial chemistry , reaction mechanism , ecology , physics , biology , thermodynamics
1,2‐Disubstituted benzimidazoles are selectively synthesized in high yields under extremely mild conditions via the condensation of o ‐phenylenediamine derivatives with aldehyde derivatives using catalytic amount of iron(III) phosphate under solvent‐free conditions. The use of readily available iron(III) phosphate as a reusable and recyclable catalyst makes this process quite simple, convenient, and environment‐friendly.