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An Efficient One‐pot Synthesis of Pyrazolone Derivatives Promoted by Acidic Ionic Liquid
Author(s) -
Zang Hongjun,
Su Qiuhong,
Guo Song,
Mo Yingming,
Cheng Bowen
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201180381
Subject(s) - chemistry , pyrazolone , ionic liquid , condensation , elemental analysis , reaction conditions , organic chemistry , catalysis , physics , thermodynamics
A new class of pyrazolone derivatives has been isolated in good to excellent yields from the 2:1 condensation reaction between 3‐methyl‐1‐phenyl‐5‐pyrazolone and arylaldehydes in the presence of ionic liquid [HMIM]HSO 4 . The compounds were characterised by their IR, NMR spectra, MS and elemental analyses. The important features of the methodology are a wide application range of substrates, higher yields and shorter reaction time.