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Copper‐catalyzed N ‐Arylation of Imidazoles with Aryl or Heteroaryl Halides Facilitated by Dimethylglyoxime in Water
Author(s) -
Wu Xiangmei,
Hu Weiya
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201180368
Subject(s) - chemistry , dimethylglyoxime , halide , benzimidazole , aryl , catalysis , imidazole , copper , medicinal chemistry , palladium , combinatorial chemistry , organic chemistry , cobalt , alkyl
A combination of CuSO 4 /dimethylglyoxime was found to be an efficient and inexpensive catalyst system for N ‐arylation of imidazole and benzimidazole with aryl halides and heteroaryl halides in water, providing the corresponding products in moderate to good yields.

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