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A One‐pot Green Synthesis of Alkylidenesuccinimides
Author(s) -
Yan Lin,
Yang Wenguo,
Li Lixin,
Shen Yang,
Jiang Zhiyong
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201180332
Subject(s) - chemistry , wittig reaction , filtration (mathematics) , solvent , reaction conditions , organic chemistry , ethanol , combinatorial chemistry , catalysis , statistics , mathematics
A mild and facile Wittig reaction between N ‐substituted maleimides and aldehydes has been developed. Various synthetically valuable alkylidenesuccinimides were obtained from this one‐pot reaction in high yields (up to 99%). The product was obtained by simple filtration and no extra purification was necessary. Ethanol, an environment‐benign solvent, was found to be a suitable reaction medium.
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