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A Convenient Method for the Preparation of 1,5‐Diaryl‐3‐(arylamino)‐1 H ‐pyrrol‐2(5 H )‐ones
Author(s) -
Ghashang Majid,
Zheng YanSong,
Shaterian Hamid Reza
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201180323
Subject(s) - chemistry , condensation , ferric , catalysis , chloride , simple (philosophy) , organic chemistry , condensation reaction , reaction conditions , environmentally friendly , combinatorial chemistry , ecology , philosophy , physics , epistemology , biology , thermodynamics
A simple and eco‐friendly method for the preparation of 1,5‐diaryl‐3‐(arylamino)‐1 H ‐pyrrol‐2(5 H )‐ones via the cyclo‐condensation reaction of aldehydes, amines and ethyl pyruvate in the presence of silica supported ferric chloride (SiO 2 ‐FeCl 3 ) as reusable heterogeneous catalyst is described. The present methodology offers several advantages such as excellent yields, simple procedure and short reaction times.