Eco‐friendly and Efficient Synthesis of 2,3‐Dihydroquinazolin‐4(1 H )‐ones | Zendy

Majid Ghashang | Zendy; Kobra Azizi | Zendy; Hamed MoulaviPordanjani | Zendy; Hamid Reza Shaterian | Zendy

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Eco‐friendly and Efficient Synthesis of 2,3‐Dihydroquinazolin‐4(1 H )‐ones

Author(s) -

Majid Ghashang,

Kobra Azizi,

Hamed MoulaviPordanjani,

Hamid Reza Shaterian

Publication year - 2011

Publication title -

chinese journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 1001-604X

DOI - 10.1002/cjoc.201180290

Subject(s) - chemistry , ammonium acetate , environmentally friendly , ammonium chloride , catalysis , solvent , ferric , organic chemistry , iron(iii) chloride , chloride , one pot synthesis , aldehyde , combinatorial chemistry , high performance liquid chromatography , ecology , biology

A simple and facile method for the synthesis of 2,3‐dihydroquinazolin‐4(1 H )‐ones through the direct cyclocondensation of one‐pot three‐component cyclocondensation of isatoic anhydride, ammonium acetate (or primary amines) and aldehydes; and anthranilamide and aldehydes using silica supported ferric chloride (SiO 2 ‐FeCl 3 ) as catalyst under solvent‐free conditions is described.

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