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Synthesis and Characterization of New 3‐(3‐Hydroxyphenyl)‐4‐ alkyl‐3,4‐dihydrobenzo[ e ][1,3]oxazepine‐1,5‐dione Compounds
Author(s) -
Osman Hasnah,
Mohammad AbdulKarimTalaq,
Yeap GuanYeow,
Adam Farook
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201180273
Subject(s) - chemistry , alkyl , ring (chemistry) , nuclear magnetic resonance spectroscopy , spectroscopy , stereochemistry , medicinal chemistry , organic chemistry , physics , quantum mechanics
A series of 3‐(3‐hydroxyphenyl)‐4‐alkyl‐3,4‐dihydrobenzo[ e ][1,3]oxazepine‐1,5‐dione compounds with general formula C n H 2 n +1 CNO(CO) 2 C 6 H 4 (C 6 H 4 OH) in which n are even parity numbers from 2 to 18. The structure determinations on these compounds were performed by FT‐IR spectroscopy which indicated that the terminal alkyl chain attached to the oxazepine ring was fully extended. Conformational analysis in DMSO at ambient temperature was carried out for the first time via high resolution 1 H NMR and 13 C NMR spectroscopy.