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Fluorescent Properties of the Amidinophenylporphyrins Interacting with DNA
Author(s) -
Wang Kai,
Li Tian,
Yu Faquan,
Zheng Yunman,
Wong WaiKwok,
Kwong Daniel W. J.,
Li Zaoying
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201100564
Subject(s) - chemistry , fluorescence , dna , porphyrin , luminescence , photochemistry , biophysics , photodynamic therapy , biochemistry , optoelectronics , organic chemistry , optics , biology , physics
5,10,15,20‐Tetrakis(4‐amidinolphenyl)porphyrin, its Zn complex and amidinolphenyl bispophyrin interacting with calf thymus DNA were investigated by fluorescence emission spectra and fluorescence life time measurements were also shown. The binding modes of these compounds were recorded and lifetimes of luminescence were measured as a function of the nature to understand the interaction with DNA. The results suggest those amidinoporphyrins are promising new photodynamic therapeutic agents.