Facile Synthesis of 3‐Substituted Isoquinolines Derivatives via Microwave‐assisted Tandem Three‐component Coupling Cyclization | Zendy

Lin Long | Zendy; Wu Qiongyou | Zendy; Huang Shaowei | Zendy; Yang Guangfu | Zendy

Premium

Facile Synthesis of 3‐Substituted Isoquinolines Derivatives via Microwave‐assisted Tandem Three‐component Coupling Cyclization

Author(s) -

Lin Long,

Wu Qiongyou,

Huang Shaowei,

Yang Guangfu

Publication year - 2012

Publication title -

chinese journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.28

H-Index - 41

eISSN - 1614-7065

pISSN - 1001-604X

DOI - 10.1002/cjoc.201100560

Subject(s) - chemistry , tandem , microwave irradiation , amine gas treating , component (thermodynamics) , palladium , catalysis , microwave , copper , coupling (piping) , combinatorial chemistry , organic chemistry , mechanical engineering , materials science , physics , quantum mechanics , engineering , composite material , thermodynamics

A novel three‐component reaction of o ‐bromobenzaldehyde, terminal alkynes and tert ‐butyl amine has been established, which proceeded smoothly to give 3‐substituted isoquinolines in good yields in the presence of palladium/copper catalysts under microwave irradiation.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research