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Michael Addition Reaction of Fluorinated Nitro Compounds
Author(s) -
Huan Feng,
Hu Huawei,
Huang Yangen,
Chen Qingyun,
Guo Yong
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201100412
Subject(s) - chemistry , nitro , adduct , michael reaction , quaternary carbon , organic chemistry , addition reaction , primary (astronomy) , medicinal chemistry , catalysis , alkyl , enantioselective synthesis , physics , astronomy
The Michael addition reactions of fluorinated nitro compounds with electron deficient olefins to give γ ‐fluoro‐ γ ‐nitro‐esters, nitriles and ketones which bear a fluorinated quaternary carbon center were reported. The reactions were promoted by TMG, affording the desired adducts in acceptable to good yields.
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