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Copper Supported on the SiO 2 Nanoparticle in Click Chemistry: An Alternative Catalytic System for Regioselective and One‐Pot Synthesis of 1,2,3‐Triazoles and β‐Hydroxytriazoles
Author(s) -
Ciyabi Hashjin Maryam,
Ciyabi Roghayeh,
Baharloui Maryam,
Hosseini Ghaffar,
Tavakoli Hamed
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201100231
Subject(s) - chemistry , click chemistry , cycloaddition , regioselectivity , sodium azide , copper , catalysis , azide , combinatorial chemistry , nanoparticle , 1,3 dipolar cycloaddition , organic chemistry , nanotechnology , materials science
In this work, readily prepared copper supported on the SiO 2 nanoparticles has been found to effectively catalyze the 1,3‐dipolar cycloaddition of a variety of azides, alkynes, epoxides and sodium azide, furnishing the corresponding 1,2,3‐triazoles and β ‐hydroxytriazoles. Click reaction proceeds in short reaction times and under mild reaction conditions, and the resulting products are obtained in good yields at ambient temperature.