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A Rapid Access to Novel and Known Benzimidazole Derivatives Using Silica Chloride as a Reusable Catalyst
Author(s) -
Karami Bahador,
Ghashghaee Vahideh,
Khodabakhshi Saeed
Publication year - 2012
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201100206
Subject(s) - chemistry , benzimidazole , catalysis , condensation , environmentally friendly , combinatorial chemistry , chloride , solvent , organic chemistry , condensation reaction , reusability , programming language , software , computer science , ecology , physics , biology , thermodynamics
A new application of silica chloride as an easily available and reusable solid acid catalyst for the synthesis of benzimidazole and its derivatives through the condensation of o ‐phenylenediamines and orthoesters under thermal and solvent‐free conditions is described. This novel and eco‐friendly method is very cheap and has many advantages including excellent yields, short reaction time, and simple work‐up procedure.