Premium
CO 2 ‐Triggered Metal Catalyst‐ and Solvent‐free Aminochlorination of Methylenecyclopropanes
Author(s) -
Qi Minghui,
Shao Lixiong,
Shi Min
Publication year - 2011
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201100073
Subject(s) - chemistry , catalysis , ring (chemistry) , halogen , solvent , metal , nitrogen , atmosphere (unit) , organic chemistry , inorganic chemistry , medicinal chemistry , polymer chemistry , meteorology , alkyl , physics
Aminochlorination of methylenecyclopropanes (MCPs) 1 can be achieved under CO 2 atmosphere using N , N ‐dichlorotoluenesulfonamine (TsNCl 2 ) as the nitrogen and halogen sources at room temperature to give the corresponding normal ring‐remaining aminochlorinated products 2 along with/without the ring‐opened aminochlorinated products 3 in moderate to good total yields. The present process takes the advantage of the green benign reaction conditions in the absence of any metal catalyst and solvent.