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Tributylammonium Halochromates/silica Gel: Simple Reagents for Oxidative Coupling of Thiols to Symmetrical Disulfides
Author(s) -
Mohammadi Mohammad Kazem,
Ghammamy Shahriare,
Zarrinabadi Soroush,
Farjam Mohammad Hossein,
Sabayan Behrang
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090363
Subject(s) - chemistry , reagent , oxidative coupling of methane , molar ratio , silica gel , chloride , inorganic chemistry , fluoride , combinatorial chemistry , nuclear chemistry , organic chemistry , catalysis
New orange solid tributylammonium halochromates, (C 4 H 9 ) 3 N + CrO 3 X − , TBAXC (X=F, Cl) are easily synthesized by the reaction of tributylammonium fluoride and chloride with CrO 3 in a 1:1 molar ratio in the presence of HF and HCl. Tributylammonium halochromates(VI) are versatile reagent for the effective and selective oxidation of organic substrates. Silica gel supported TBAFC and TBACC are versatile reagents for the effective and selective oxidation of organic substrates, in particular, thiols, under mild conditions. Considerable improvements are observed in the presence of the absorbent, making the work‐up much more convenient.