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Synthesis of Hollow Gold Nanospheres and Their Applications in Surface‐enhanced Raman Scattering and DNA Biosensor
Author(s) -
Meng Qi,
Li Hui,
Yang Haifeng,
Li Hexing
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090336
Subject(s) - rhodamine 6g , chemistry , raman scattering , raman spectroscopy , colloidal gold , nanotechnology , biosensor , fluorescence , rhodamine , nanoparticle , molecule , chemical engineering , optics , materials science , organic chemistry , biochemistry , physics , engineering
Hollow gold nanospheres (HGNs) with nanopinholes were prepared by chemical reduction of HAuCl 4 with aqueous KBH 4 in the presence of the Bu 4 PBr template. The HGNs could be served as substrates for surface‐enhanced Raman scattering (SERS), which exhibited much higher surface enhancement than the solid gold nanoparticles in case of Rhodamine 6G as a molecule probe. Moreover, the HGNs could also be used in the modified electrode to detect DNA and superior to the solid counterpart of the similar size. Based on the detailed characterizations by transmission electron micrograph (TEM), field emission scanning electron micrograph (FESEM) and UV‐visible absorption spectroscopy, a plausible mechanism for forming HGNs was proposed. Meanwhile, the promoting effect of the hollow gold nanospheres on the SERS was discussed briefly.