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A New Sensor for Simultaneous Determination of Tyrosine and Dopamine Using Iron(III) Doped Zeolite Modified Carbon Paste Electrode
Author(s) -
Babaei Ali,
Zendehdel Mojgan,
Khalilzadeh Balal,
Abnosi Mohammad
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090328
Subject(s) - detection limit , chemistry , carbon paste electrode , electrode , differential pulse voltammetry , analytical chemistry (journal) , linear range , selectivity , chromatography , nuclear chemistry , cyclic voltammetry , electrochemistry , catalysis , organic chemistry
A new chemically modified electrode is constructed based on iron(III) doped zeolite modified carbon paste electrode (Fe 3+ Y/ZMCPE). The new sensor could be used for the simultaneous determination of the biologically important compounds dopamine (DA) and tyrosine (Tyr). The measurements are carried out using differential pulse voltammetric (DPV) method. The prepared modified electrode shows voltammetric responses of high sensitivity, selectivity and stability for DA and Tyr under optimal conditions, which makes it a suitable sensor for simultaneous trace detection of DA and Tyr in solution. Application of the DPV method demonstrates that in the Briton Robinson buffer solutions (pH=5) containing 50 µmol/L Tyr, there is a linear relationship between the oxidation peaks and the concentrations of DA over the range of 0.1–200 µmol/L, with a detection limit of 0.05 µmol/L (S/N=3). For Tyr a linear correlation between oxidation peak current and concentration of Tyr over the range of 0.5–200 µmol/L (containing 50 µmol/L DA), with a detection limit of 0.08 µmol/L is obtained. The analytical performances of this sensor are evaluated for the detection of DA and Tyr in human serum and a medicine.