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An Elimination Approach to the Synthesis of (+)‐Scorodonin
Author(s) -
Zhang Yan,
Wu Yikang
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090277
Subject(s) - stereocenter , chemistry , allylic rearrangement , chirality (physics) , sulfoxide , optically active , stereochemistry , combinatorial chemistry , enantioselective synthesis , organic chemistry , catalysis , chiral symmetry breaking , physics , quantum mechanics , quark , nambu–jona lasinio model
1,2‐Elimination of optically‐active vinyl sulfoxide‐allylic acetates led to corresponding allenynes in excellent yields. When the chirality of the sulfinyl group "matched" that at the allylic position, the chirality at the allylic stereogenic center could be efficiently transferred to the allenic axis.