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Study on the Reactions of 3‐Bromo‐4‐ethoxy‐1,1,1‐trifluoro‐ 3‐buten‐2‐one with Benzenethiols Promoted by InCl 3 ·4H 2 O
Author(s) -
Zhao Jingwei,
Song Tao,
Jiang Huiling,
Xu Liangzhong,
Zhu Shizheng
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090275
Subject(s) - chemistry , alkoxy group , reactivity (psychology) , medicinal chemistry , product (mathematics) , substitution reaction , stereochemistry , organic chemistry , alkyl , medicine , alternative medicine , geometry , mathematics , pathology
Abstract In the presence of InCl 3 ·4H 2 O, the reaction of 3‐bromo‐4‐ethoxy‐1,1,1‐trifluoro‐3‐buten‐2‐one 2 with a series of benzenethiols proceeds readily and gave both the addition‐elimination product 3‐bromo‐1,1,1‐trifluoro‐4‐thiophenyl‐but‐3‐en‐2‐one and substitution product 1,1,1‐trifluoro‐3,4‐bis‐thiophenyl‐but‐3‐en‐2‐one. The reactivity of benzenethiols is discussed in terms of their substituted group.