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Construction and Biofunction of 3‐Dimensional Self‐assembly Collagen Nanostructure on PLLA Substrate
Author(s) -
Xu Shouhong,
Liu Aiping,
Lin Xiaoxiao,
Liu Honglai,
Yonese Masakastu
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090266
Subject(s) - chemistry , adsorption , substrate (aquarium) , nanostructure , biomineralization , chemical engineering , atomic force microscopy , self assembly , ellipsometry , nanotechnology , thin film , organic chemistry , materials science , engineering , oceanography , geology
A 3‐dimensional and multi‐layered network nanostructure of collagen assembled on the poly( L ‐lactic) acid (PLLA) substrate was reported. Collagen adsorption layers were prepared by dipping PLLA substrates into collagen solutions with various pH. The influences of adsorption interval, pH of collagen solutions and properties of PLLA substrate on the adsorption behavior of collagen were investigated by using atomic force microscopy and ellipsometry measurements. It was found that the multiple association degrees of collagen molecules in solution at a certain pH value seemed to play an important role in the adsorption process. The distinct adsorption behavior determined a specific 3‐dimensional structure formed at the interface. Furthermore, calcium carbonate (CaCO 3 ) can be biomimetically crystallized by the inducement of biomineralization on these collagen layers.