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1,4‐Diaza‐bicyclo[2,2,2]octane as a Novel and Efficient Catalyst for the Synthesis of 3,4,6‐Trisubstituted 2‐Pyridone Derivatives
Author(s) -
Heravi Majid M.,
Tahershamsi Leili,
Oskooie Hossein A.,
Baghernejad Bita
Publication year - 2010
Publication title -
chinese journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.28
H-Index - 41
eISSN - 1614-7065
pISSN - 1001-604X
DOI - 10.1002/cjoc.201090130
Subject(s) - chemistry , dabco , octane , bicyclic molecule , catalysis , 2 pyridone , condensation , medicinal chemistry , organic chemistry , combinatorial chemistry , physics , thermodynamics
3,4,6‐Trisubstituted 2‐pyridone derivatives have been synthesized in good to excellent yields through a condensation reaction of various 1,3‐diketones with amides in the presence of 1,4‐Diaza‐bicyclo[2,2,2]octane (DABCO) at reflux temperature.